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Chloroquine and Cinchonine Affect Rat Vascular Smooth Muscle Tonus Through Calcium Channels – In Silico and In Vitro Approaches

research Chloroquine and Cinchonine Affect Rat Vascular Smooth Muscle Tonus Through Calcium Channels – In Silico and In Vitro Approaches

January 2024 in “Bratislavské lekárske listy/Bratislava medical journal”

Chloroquine and cinchonine relax rat blood vessels by affecting calcium channels, with chloroquine needing caution in heart patients.

Skin Morphogenesis by Coupling Biochemical-Bioelectric Signals: Calcium Oscillations Coordinate Dermal Cell Movement by Epidermis-Derived SHH Signaling During Feather Bud Orientation

research Skin Morphogenesis by Coupling Biochemical-Bioelectric Signals: Calcium Oscillations Coordinate Dermal Cell Movement by Epidermis-Derived SHH Signaling During Feather Bud Orientation

April 2019 in “Journal of Investigative Dermatology”

Calcium signals and SHH guide the direction of feather growth in chicken skin.

research Emerging Roles for Ion Channels in Ovarian Cancer: Pathomechanisms and Pharmacological Treatment

29 citations , February 2021 in “Cancers”

Ion channels play a key role in ovarian cancer growth and treatment resistance.

research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

140 citations , February 2014 in “Neuron”

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

State-Dependent Signaling by Cav1.2 Regulates Hair Follicle Stem Cell Function

research State-Dependent Signaling by Cav1.2 Regulates Hair Follicle Stem Cell Function

27 citations , June 2013 in “Genes & development”

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

View more "voltage-gated calcium channels" in research →

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community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

in Technology 10 upvotes 2 months ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.