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Research

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research Review of the current understanding of the effect of ultraviolet and visible radiation on hair structure and options for photoprotection

22 citations , July 2004 in “International Journal of Cosmetic Science”

This article reviews the impact of UV radiation and visible light on human hair structure and summarizes protective strategies, reporting no new clinical results.

research 644 Response of distinct human dermal fibroblast lineages to visible radiation: Potential for differential light-based therapy

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that while 450nm blue light can inhibit collagen and induce oxidative stress in dermal fibroblasts, 850nm near-infrared light may enhance metabolic activity without causing oxidative damage, suggesting potential for tailored light therapies in skin treatments.

research Measuring oxidative damage to human hair from solar radiation and pollution: A critical review

May 2026 in “Journal of Photochemistry and Photobiology”

This review found that solar radiation, pollution, and trace metals cause significant damage to human hair, with factors like UVB radiation primarily affecting light-colored and bleached hair; most data were derived from in vitro and ex vivo simulations.

research Photoageing of Hair Fiber and Photoprotection

18 citations , March 2009 in “Skin pharmacology and physiology”

This study found that sunlight exposure causes significant structural and chemical damage to hair, including cuticle loss, cortex damage, and discoloration, with water playing a major role in discoloration of brown hair.

research Melasma, a photoaging disorder

144 citations , December 2017 in “Pigment cell & melanoma research”

This review suggests that melasma may be a photoaging skin disorder affecting genetically predisposed individuals, which could significantly influence its treatment and prevention strategies.

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Community Join

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community Lots of shedding after adding bica 50 mg daily

in Transgender 119 upvotes 1 year ago

Switching from spironolactone to bicalutamide caused severe hair shedding, despite using treatments like dutasteride, minoxidil, and estradiol injections. The user is experiencing androgenetic alopecia and is seeking solutions to stop the hair loss.

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 2 years ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community 6 Months Into Dut Progress Pictures

102 upvotes 1 year ago

Switching from finasteride to dutasteride caused significant shedding but minimal side effects. The user plans to continue dutasteride for 12 months despite concerns about hair density.

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Learn

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learn Rapamycin

Are there any visible side effects when using rapamycin cream or serum on the scalp? No study has tested rapamycin on the scalp; in facial trials skin reactions were common (64% vs 29% placebo; Aitken et al. 2023, PMID 37463422).

learn Hair Transplant

Will there be visible scarring after a hair transplant? Every transplant leaves scars. FUE leaves many small dot scars that are usually hidden by hair but can show when it is cut very short, and FUT leaves a line scar.

learn Pyrilutamide

How long does it take to see visible results when using pyrilutamide topically? No published trial reports when pyrilutamide users first notice a change; its sponsor's studies measured results at 24 weeks, and all of those figures come from company announcements rather than peer-reviewed papers. Pyrilutamide is an unapproved experimental compound.

learn white tea

Do white tea products produce visible results, and how long would it take to tell? There is no human evidence that white tea products change hair; any hair effect would take months to judge, and none has been shown.

learn Procyanidin

How long should Procyanidin be used before seeing visible improvements in hair volume or density? The three published trials of topical procyanidin alone measured results at four to twelve months, so any visible change would take at least several months. All were small, in men only, and run by the company that developed the ingredient; procyanidin is not an approved hair-loss treatment.

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