34 citations
,
December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology”
This study observed that rat vibrissa hair follicles cultured in vitro showed morphological changes suggesting cyclical activity but remained blocked in the pro-anagen stage.
3 citations
,
August 2000 in “Anatomia Histologia Embryologia”
In this study, prenatal exposure to a non-teratogenic dose of all-trans-retinoic acid showed no adverse effects on vibrissalfollicle development in NMRI mice.
PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.
Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.