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research Odontogenic Potential of Mesenchymal Cells from Hair Follicle Dermal Papilla

42 citations , August 2008 in “Stem Cells and Development”

This study found that mesenchymal cells from adult mouse whisker follicles differentiated into odontoblast-like cells, demonstrating odontogenic potential in a specialized microenvironment both in vitro and in vivo.

research Role of hair papilla cells on induction and regeneration processes of hair follicles

57 citations , November 1998 in “Wound Repair and Regeneration”

This research observed that dermal papilla cells have the potential to regenerate hair bulbs under preferred environmental conditions when associated with dermal sheath cells or exposed to specific growth factors.

research Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells

10 citations , January 2014 in “BioMed research international”

In this study, dermal papilla cells from rat vibrissae showed potential for treating CNS injuries by secreting neurotrophic factors and promoting neuronal differentiation more effectively than bone marrow mesenchymal stem cells.

research Heterotypic cell contacts and basal lamina morphology during hair follicle development in the mouse: a light, scanning, and electron microscopic study at the site of tissue interaction

13 citations , December 1983 in “Canadian journal of zoology”

This study found that mesenchymal cell processes from the dermal papilla contact epithelial hair matrix cells through gaps in the basal lamina during hair matrix cell differentiation in mouse vibrissa follicles.

research The germinative epithelium of sheep vibrissae and wool follicles has extensive proliferative potential but is dependent on the dermal papilla

1 citations , January 2012 in “International journal of trichology”

This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.

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community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

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Experimental compound that activates hair-growth signals, tested only in animals

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