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This study found that using a vibration anesthetic device during scalp mesotherapy significantly reduced pain in patients with androgenetic alopecia and alopecia areata compared to the non-vibration side.

This study found that using topical anesthetic was more effective than a vibrating device in reducing discomfort from dental injections.

This study found that the Leni wand device, which combines cold and vibration, was more effective at reducing pain from local anesthesia injections during hair transplant surgery than a device using only vibration, although results were obtained solely from a male participant group.

This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.

This study found that using vibration during supraorbital/supratrochlear nerve blocks in hair restoration surgery significantly reduced pain levels compared to not using vibration, with patients reporting lower Wong-Baker Faces Pain scores when vibration was applied.