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Glossary Microvessel Density

number of tiny blood vessels in a specific tissue area

Microvessel Density (MVD) refers to the number of tiny blood vessels, or microvessels, within a specific area of tissue. It is often used as a measure in medical research to assess the extent of angiogenesis, which is the formation of new blood vessels, particularly in the context of tumor growth and other pathological conditions. High MVD can indicate increased blood supply to a tumor, which may correlate with more aggressive disease and poorer prognosis.

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Research

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Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Microvessel Density

research Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Micro Vessel Density

January 2024

In this animal study, rats treated with recombinant human growth hormone (at both low and high doses) experienced quicker burn wound healing than controls, with increased micro vessel density and altered expression of vascular endothelial growth factor, alongside changes in oxidative stress and inflammation markers.

research A new model of blood vessel remodeling

January 2002

This study observed that hair follicle cycling in mouse skin involves physiological vascular remodeling, with VEGF playing a key role, suggesting potential therapeutic approaches for hair growth disorders.

research Macrophages in Skin Wounds: Functions and Therapeutic Potential

56 citations , November 2022 in “Biomolecules”

This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.

The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization, and Hair Growth in a Porcine Model

research The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization and Hair Growth in a Porcine Model

16 citations , April 2016 in “PLoS ONE”

In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.

research Anagen Hair Follicles Transplanted into Mature Human Scars Remodel Fibrotic Tissue

1 citations , January 2021 in “SSRN Electronic Journal”

In this pilot study, the researchers observed that transplanting anagen hair follicles into human scars can promote remodeling of fibrotic tissue and inhibit pro-fibrotic factors, offering potential new treatments for mature scars.

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Community Join

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community Grow Gorgeous Intense Hair Density Serum, 2.02 fl oz, 2-pack from Costco

1 year ago

The user is considering using "Grow Gorgeous Intense Hair Density Serum" alongside Minoxidil and is currently taking Finasteride. Some users doubt the serum's effectiveness, while others suggest it may help with hair strength and thickness, but opinions are mixed.

community Can one of you smarty pants explain the PP405 results? Why did they choose to highlight that 31% had 20% increase in density? What about the other 69%? What about other ±% in density? Why is this considered a great result? Thanks.

13 upvotes 10 months ago

PP405 shows promise in reactivating dormant hair follicles, with 31% of users experiencing a 20% increase in hair density in a short period. It may work faster than minoxidil and without side effects, but its long-term effectiveness is still uncertain.

community 2 years on fin and amazed by the results

in Finasteride/Dutasteride 132 upvotes 1 year ago

Finasteride significantly improved hair density and reduced hair loss for the user over two years, with plans to switch to dutasteride for long-term benefits. The user experienced no shedding or side effects and obtained finasteride through a private prescription in the UK.

community Serum based on plant extracts boosts hair growth in weeks.

44 upvotes 11 months ago

A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

community Debunking Androgenetic Theory (Hair Transplants)

in Research/Science 25 upvotes 2 years ago

The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

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