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Oral Administration of Low-Dose Bisphenol A Promotes Proliferation of Ventral Prostate and Upregulates Prostaglandin D2 Synthase Expression in Adult Rats

research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D₂ synthase expression in adult rats

14 citations , June 2015 in “Toxicology and Industrial Health”

This study found that low doses of bisphenol A may increase proliferation of the ventral prostate in adult rats by altering the estrogen to androgen ratio and gene expression.

research In vitro [7-3H]-testosterone metabolism by the rat ventral prostate—Effect of some exogenous compounds

12 citations , February 1975 in “Journal of Steroid Biochemistry”

research 4‐MAPC, a 5α‐Reductase Inhibitor, Reduces Rat Ventral Prostate Weight, DNA, and Prostatein Concentrations

7 citations , September 1991 in “Journal of Andrology”

In this study, 4‐MAPC treatment reduced ventral prostate weight in rats primarily through decreased synthetic activity, with testosterone propionate increasing prostate weight and activity at pharmacologic doses.

research Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment

26 citations , July 1995 in “Neurobiology of Aging”

Finasteride affects prostate weights and pituitary activity differently with age.

research FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects

17 citations , June 1996 in “The Journal of Steroid Biochemistry and Molecular Biology”

In this study, FCE 28260 showed greater potency than finasteride in inhibiting 5α-reductase enzymes and reducing prostate DHT levels in rats.

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community abusing caffeine boosts DHT levels!

in Research/Science 1 upvotes 1 year ago

Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 3 years ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

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