November 2024 in “Journal of Investigative Dermatology” This study identified PTEN as a key regulator in non-healing venous leg ulcers, suppressing immune responses and lymphangiogenesis, suggesting its potential as a therapeutic target for promoting VLU healing.
April 2026 in “Frontiers in Bioengineering and Biotechnology” This study found that a cellulose membrane significantly shortened the healing time and reduced the ulcer area in patients with chronic venous leg ulcers compared to a standard antimicrobial dressing.
4 citations
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January 2016 in “JAMA Dermatology” This article discusses potential benefits of increasing active range of motion in the care of venous leg ulcers but reports no new clinical results.
56 citations
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March 2016 in “International Wound Journal” This review concludes that autologous split-thickness skin grafting remains the gold standard for safety and efficacy in treating chronic leg ulcers, with greater success in venous ulcers.
6 citations
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June 2017 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This study reported that using hair follicles from the scalp in punch-type grafts improved healing in chronic venous ulcers compared to traditional hairless punch grafts.