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This study developed a vascularized full-thickness skin equivalent with a complex vascular network, enhancing its predictiveness for topical and systemic drug applications in dermatology research.

This study developed a 3D bioprinted skin model to mimic pemphigus vulgaris, providing a tool to study disease mechanisms and test targeted therapies by reproducing the architecture and pathogenic disruptions of native skin.

Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.

This study observed that using ex vivo gene therapy to modify skin cells in a pre-graft model improved dermal-epidermal junction adhesion strength and maintained collagen production over time, suggesting a potential treatment approach for recessive dystrophic epidermolysis bullosa skin wounds.

This review summarizes recent advances in organoid technology for generating tissue models from the three germ layers and reports no new experimental results.