5 citations
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November 2012 in “Journal of Clinical Psychopharmacology” This case report describes an 80-year-old man who developed valproate toxicity and functional decline after starting isoniazid, highlighting a potential drug interaction in elderly patients.
May 2022 in “Indian Journal of Pharmacology” This case report highlights a rare instance of valproate-induced hypertensive urgency in a 2-year-old girl, with improvement after stopping the medication.
February 2025 in “ACS Applied Materials & Interfaces” This study found that a novel choline-based valproic acid ionic liquid significantly enhances transdermal penetration and promotes hair regrowth without causing irritation or toxicity, offering a promising treatment option for alopecia.
16 citations
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October 1994 in “PubMed” This review, drawing on literature and personal experience, suggests that sodium valproate is a safe and effective antiepileptic drug for various epileptic conditions in children and adults, including the elderly.
6 citations
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June 2013 in “Toxicological Research” This study found that topical valproate has minimal potential to cause skin irritation, suggesting it can be applied safely to human skin.