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research Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V

6 citations , July 2021 in “Frontiers in Genetics”

This study identified a new heterozygous missense variant in CST6 associated with autosomal dominant keratosis follicularis spinulosa decalvans in an Austrian family, affecting epidermal differentiation and hair formation.

research Milestones in Photocarcinogenesis

29 citations , July 2013 in “Journal of Investigative Dermatology”

This review explores the mechanisms by which UV radiation causes skin cancer, highlighting UV-induced DNA damage and its implications for cancer prevention strategies, but reports no new findings.

research Acquired Localized Longitudinal Pachyonychia and Onychomatrical Tumors: A Comparative Study to Onychomatricomas (5 Cases) and Onychocytic Matricomas (4 Cases)

18 citations , April 2016 in “American Journal of Dermatopathology”

This case series highlights that nail clipping can aid in early detection and surgical planning of onychomatrical tumors by distinguishing between benign and potentially malignant growths based on the cavities' average dimensions.

research Actinic keratosis: A clinician’s guide to diagnosis and treatment

September 2026 in “Cleveland Clinic Journal of Medicine”

This review outlines an individualized approach for clinicians to treat actinic keratoses based on lesion number, area, and patient preference, emphasizing early intervention to prevent progression to skin cancer.

research Cutaneous manifestations of dabrafenib (GSK2118436): a selective inhibitor of mutant BRAF in patients with metastatic melanoma

173 citations , July 2012 in “British Journal of Dermatology”

This study found that the administration of the mutant BRAF inhibitor dabrafenib in patients with metastatic melanoma was associated with various skin lesions, including keratinocytic proliferation that sometimes showed low-grade malignancy features.

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community Oral v topical Min & Dutasteride

16 upvotes 1 month ago

The user experienced hair loss after switching from topical to oral minoxidil and adding dutasteride, leading to doubts about its effectiveness. They are considering returning to RU58841 or topical minoxidil due to continued shedding and mental distress.

community Day 1 v 3 month progress. Topical Spray used in the UK.

68 upvotes 3 weeks ago

A user in the UK reports significant hair growth progress after three months using a topical spray containing Minoxidil, Finasteride, and Tretinoin, applied daily. They recommend the product from e-Surgery, noting no side effects and using Biotin shampoo every two days.

community Is 0.1%w/v topical fin overkill if taking oral 0.5mg fin?

in Finasteride/Dutasteride 2 upvotes 7 months ago

The conversation discusses whether using 0.1% topical finasteride alongside 0.5 mg oral finasteride is excessive, with suggestions to choose either oral or topical treatment. The user also uses 5% minoxidil and mentions concerns about alcohol-based solutions due to seborrheic dermatitis.

community Best reversing hairloss protocol i’v seen - do you trust it?

in Treatments 104 upvotes 1 year ago

The conversation discusses a hair loss protocol and compares it to using finasteride and minoxidil. It suggests that while the protocol includes some good advice, it may not surpass the effectiveness of established treatments like finasteride and minoxidil.

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