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Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins

research Experimental, molecular docking investigations and bioavailability study on the inclusion complexes of finasteride and cyclodextrins

23 citations , June 2017 in “Drug Design Development and Therapy”

This study found that the dimethyl-β-cyclodextrin inclusion system significantly improved the solubility and bioavailability of finasteride compared to the drug alone, enhancing its absorption rate.

research Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

88 citations , August 1998 in “Carcinogenesis”

This study found that overexpression of ornithine decarboxylase and activated Ha-ras together led to a high rate of tumor development in a mouse model without additional carcinogens.

research Pro-inflammatory Vδ1+T-cells infiltrates are present in and around the hair bulbs of non-lesional and lesional alopecia areata hair follicles

23 citations , September 2020 in “Journal of Dermatological Science”

This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.

research Reconstruction of large alopecia with old technique: V-Y-S plasty

2 citations , April 2014 in “International Wound Journal”

The authors reported that V-Y-S plasty was a safe one-stage method for reconstructing very large scalp alopecia following burns or surgeries.

research Human dermal Vδ1 + T-cells recognize “stressed” HFs and may induce alopecia areata

1 citations , April 2017 in “Journal of Dermatological Science”

This study suggests that dermal Vδ1+ T-cells in human skin can promote alopecia areata by interacting with stressed hair follicles, potentially providing a target for new treatments.

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Community Join

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community Oral v topical Min & Dutasteride

16 upvotes 1 month ago

The user experienced hair loss after switching from topical to oral minoxidil and adding dutasteride, leading to doubts about its effectiveness. They are considering returning to RU58841 or topical minoxidil due to continued shedding and mental distress.

community Day 1 v 3 month progress. Topical Spray used in the UK.

68 upvotes 1 week ago

A user in the UK reports significant hair growth progress after three months using a topical spray containing Minoxidil, Finasteride, and Tretinoin, applied daily. They recommend the product from e-Surgery, noting no side effects and using Biotin shampoo every two days.

community Is 0.1%w/v topical fin overkill if taking oral 0.5mg fin?

in Finasteride/Dutasteride 2 upvotes 6 months ago

The conversation discusses whether using 0.1% topical finasteride alongside 0.5 mg oral finasteride is excessive, with suggestions to choose either oral or topical treatment. The user also uses 5% minoxidil and mentions concerns about alcohol-based solutions due to seborrheic dermatitis.

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