112 citations,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
1 citations,
January 2013 in “MedChemComm” PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
55 citations,
June 2014 in “Nature Communications” Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
26 citations,
September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.