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P21Waf1/Cip1 Is Differentially Expressed in Epidermal Versus Follicular Melanocytes and Melanoma Cells and Is Phenotypically Regulated by UVB-Mediated Apoptosis

research P21Waf1/Cip1 Is Differentially Expressed in Epidermal Versus Follicular Melanocytes and Melanoma Cells and Is Phenotypically Regulated by UVB-Mediated Apoptosis

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.

research Identification of MicroRNAs Involved in Growth Arrest and Cell Death in Hydrogen Peroxide-Treated Human Dermal Papilla Cells

12 citations, April 2014 in “Molecular Medicine Reports”

Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.

research Cell Death in the Skin: Mechanisms and Implications

120 citations, February 2009 in “Apoptosis”

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

research Cell Death in Skin Function, Inflammation, and Disease

12 citations, August 2022 in “Biochemical Journal”

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

research Protective Role of Melatonin and Its Metabolites in Skin Aging

32 citations, January 2022 in “International Journal of Molecular Sciences”

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

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community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community 5 month update on my all natural protocol

in Update 7 upvotes 6 years ago

The user updated on their all-natural hair loss protocol, which includes massages, LLLT, Ashwagandha, Supergreens mix, Vitamin D, Castor Oil + DMSO, a specific diet, and headstands. They reported some hair regrowth and improved hair quality, with plans to continue the regimen and monitor results.

community Sucess story for you guys, pics are 10+ years apart.

in Progress Pictures 311 upvotes 8 months ago

A user shared a success story showing hair regrowth over 10 years, attributing it to quitting creatine and taking 0.5mg finasteride. Some commenters were skeptical about creatine's impact, while others inquired about side effects, and the original poster reported no negative effects from finasteride.

community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

in Minoxidil 78 upvotes 8 months ago

A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

community Still not sure why men think diet has nothing to do with hair loss when scientific is quite the opposite [Link]

25 upvotes 6 years ago

Diet can influence hair health, but male pattern baldness (MPB) is primarily genetic. Treatments discussed include Minoxidil, finasteride, and RU58841.

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