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      research Update and Future of Systemic Acne Treatment

      117 citations , January 2003 in “Dermatology”
      This review discusses various treatments for moderate-to-severe acne, highlighting antibiotics, oral isotretinoin, and hormonal therapies, with a focus on resistance and emerging treatment options but reports no new clinical results.

      research Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis

      78 citations , June 2021 in “Dermatology and Therapy”
      This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.

      research Update and Future of Hormonal Therapy in Acne

      78 citations , January 2003 in “Dermatology”
      This article reviews hormonal therapy as a treatment for acne in women and suggests that emerging research on hormone synthesis and metabolism in the skin could guide future drug development.

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      community (UPDATE, 22M) Receding hairline following period of insane gains.

       45 upvotes 2 weeks ago
      A user is experiencing hair shedding after initially gaining hair while using 1mg finasteride daily and topical minoxidil twice a day. Others in the conversation suggest that shedding cycles are common and recommend continuing the treatment, possibly adding oral minoxidil, and consulting a dermatologist if needed.

      community Update from my previous post, doctor agreed to up my dose.

       16 upvotes 2 weeks ago
      The user increased their oral minoxidil dose to 5mg daily, resulting in noticeable hair growth without side effects. They do not use finasteride or other DHT blockers, despite suggestions from others.

      community Update: approx 3 years on oral finasteride 1mg and oral minoxidil 2.5mg

       16 upvotes 2 weeks ago
      A 49-year-old man experienced positive results in treating crown hair loss with daily 1mg finasteride and 2.5mg minoxidil over three years. He noticed progress after 12 months, with significant improvement by 18 months, and no side effects from finasteride.

      community Update after 15 years on finasteride and 4 on dutasteride

       210 upvotes 2 weeks ago
      A 55-year-old male has been managing hair loss with finasteride for 15 years and switched to dutasteride in 2022 due to thinning. He also uses minoxidil, PRP treatments, and ketoconazole shampoo, and is considering a shorter hairstyle for more volume.