28 citations
,
February 1999 in “Journal of Investigative Dermatology” This study found that neonatal mice without the urokinase-type plasminogen activator (uPA) gene had reduced epidermal proliferation rates, suggesting uPA's involvement in promoting keratinocyte proliferation.
10 citations
,
January 2008 in “Biological and Pharmaceutical Bulletin” This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.
2 citations
,
July 2004 in “Cell Biology International” This study found that urokinase plasminogen activator (uPA) is elevated in hyperproliferative hair follicle keratinocytes in mice, and its inhibition significantly reduces their proliferation.
658 citations
,
June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
53 citations
,
September 2020 in “Stem Cell Research & Therapy” This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.