113 citations
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March 2018 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
2 citations
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November 2022 in “Bioscience Reports” Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.
3 citations
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March 2019 in “Chinese Medical Journal” CO2 fractional laser therapy may help regrow hair without scarring by affecting certain inflammatory and growth-related molecules.
April 2017 in “Journal of Dermatological Science” The study investigated the mechanisms of hair loss in acrodermatitis enteropathica (AE) using zinc-adequate (ZA) and zinc-deficient (ZD) mice. Although ZD mice did not show obvious hair loss, their hair was sparser compared to ZA mice, and their hair cycle was disrupted, remaining in the telogen stage. Depilation-induced anagen initiation was absent in ZD mice but restored with zinc supplementation, indicating reversible impairment of hair cycle functions due to zinc deficiency. Dermal papilla (DP) cells in ZD mice were atrophic and lacked tissue-nonspecific alkaline phosphatase (TNAP) activity, a zinc-dependent enzyme crucial for hair regeneration. Additionally, platelet-derived growth factor (PDGF) expression was significantly reduced in ZD dermis, suggesting that zinc deficiency led to decreased PDGF production and downregulated TNAP activity, causing hair cycle disruption and impaired hair regeneration.
39 citations
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January 2020 in “Frontiers in Genetics” PDGFC gene may help select goats with desirable curly wool traits.