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research Scd1 ab-Xyk : a new asebia allele characterized by a CCC trinucleotide insertion in exon 5 of the stearoyl-CoA desaturase 1 gene in mouse

12 citations , July 2004 in “Molecular genetics and genomics”

This study identifies a new mutation in the Scd1 gene in a strain of Kunming mice, causing skin and hair defects with the mildest impact among similar mutations.

research Characteristic analysis of sebaceous nevus using dermoscopy and reflectance confocal microscopy

2 citations , July 2018 in “Chinese Journal of Dermatology”

This study reported that imaging characteristics of sebaceous nevus vary significantly by age group, revealing dynamic developmental changes that can be effectively identified through dermoscopy and reflectance confocal microscopy, offering noninvasive diagnostic potential.

research Biochemistry of epidermal stem cells

26 citations , July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

research Congenital Hypotrichosis in Japanese White Strain (JW-NIBS) Rabbits.

2 citations , January 2000 in “Journal of Toxicologic Pathology”

This study identified a single autosomal recessive gene responsible for hypotrichosis in a mutant rabbit strain, affecting hair growth and causing epidermal and hair follicle abnormalities.

research Percutaneous drug delivery to the hair follicle

1 citations , January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology”

This review discusses the roles of hair follicles and sebaceous glands in percutaneous transport and reports no new results, noting a lack of adequate models and methodologies.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

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