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DDB1 and CUL4 associated factor 17

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research Molecular Elements of the Regulatory Control of Keratin Filament Modulator AHF/Trichohyalin in the Hair Follicle

7 citations, July 2008 in “Experimental Dermatology”

The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.

research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One

10 citations, July 2022 in “Journal of Medicinal Chemistry”

Adding a second method to PROTACs could improve cancer treatment.

Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators in Differentiation, Proliferation, and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

research Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators in Differentiation, Proliferation, and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

January 2023 in “Frontiers in bioscience”

Artemis protein may help control hair growth and health by influencing cell processes.

research LO-010 Relationship Between The EULAR/ACR Classification Criteria And Organ Damage In Systemic Lupus Erythematosus

July 2023

Higher EULAR/ACR scores in SLE patients predict more organ damage.

research Small Molecule Inhibitors and Inflammatory Skin Diseases

March 2018 in “Suez Canal University Medical Journal”

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

View more "ubiquitin-dependent proteolysis" in research →

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community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 123 upvotes 11 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 136 upvotes 7 months ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.