February 2026 in “Journal of the American Academy of Dermatology” In this study, researchers characterized the clinical features of ophiasis, an uncommon type of alopecia areata, and proposed a new subtype classification that may help predict treatment response and guide management, noting that ophiasis generally has a chronic and refractory nature.
30 citations
,
August 2015 in “JAAD case reports” This case report describes a patient with corticosteroid-resistant ophiasis alopecia areata who experienced prompt hair regrowth after receiving platelet-rich plasma injections.
13 citations
,
November 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that topical clobetasol propionate cream provided a modest improvement in hair regrowth for alopecia areata patients, though those with atopy had higher relapse rates after treatment completion.
July 2025 in “Journal of Dermatology Research Reviews & Reports” In this case study, a 10-year-old girl with infantile ophiastic alopecia areata and ciliary madarosis showed excellent hair and eyelash regrowth after 56 days of treatment involving oral corticosteroids, topical minoxidil, and clobetasol hair lotion, following an initial diagnosis and psychological evaluation.
September 2023 in “Cureus” This case report describes a four-month-old infant with atypical alopecia areata following a cultural head-shaving ritual, who showed improvement with topical triamcinolone treatment, though not full symptom resolution, highlighting the rarity and complexity of managing AA in infants.