research Structure of human type II 5 alpha-reductase gene.
This article discusses the structure of the human type II 5 alpha-reductase gene and reports no new experimental results.
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research Structure of human type II 5 alpha-reductase gene
This study details the isolation and characterization of the human type II 5 alpha-reductase gene, which may play a role in male pseudohermaphroditism, prostate cancer, and benign prostatic hyperplasia.
research The long-term effect of specific type II 5alpha-reductase inhibition with finasteride on bone mineral density in men: results of a 4-year placebo controlled trial.
In this study, long-term use of finasteride did not negatively impact bone mineral density in men with benign prostatic hyperplasia over a 4-year period.
research Expression and Activity Assay of Human Steroid 5 Alpha-Reductase Type II in CHO Cells
This study found that finasteride effectively inhibits the enzymatic activity of human steroid 5 alpha reductase type II in newly established CHO cell lines.
research In Silico Structure-Based Drug Design Approach To Evaluate Quercetin And Kaempferol As Dual Inhibitors Of Jak3 Kinase And 5-Alpha Reductase Type II with ADMET Profiling
In this study, quercetin and kaempferol, two plant-derived flavonoids, showed stronger binding affinities to JAK3 kinase and moderate binding to 5-alpha reductase type 2, suggesting their potential as natural treatments for androgenetic alopecia, with quercetin demonstrating suitable properties for topical application.
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5 / 1000+ resultscommunity Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.
Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.
community I stopped finasteride and minoxidil and I regret it
The user regrets stopping finasteride and minoxidil due to increased hair loss. They have resumed these treatments and are considering a hair transplant.
community UPDATE: now 5 months on Dut and continuing to regress aggressively
The user is experiencing significant hair loss after switching from finasteride to dutasteride for five months. Suggestions include that the hair loss might be a normal shedding phase, with some recommending continuing the treatment for up to 24 months or considering alternatives like RU58841.
community 5 years on topical finasteride, 3.5 years on oral minoxidil; now changing from finasteride to dutasteride
A 66-year-old male experienced significant hair regrowth using topical finasteride for 5 years and oral minoxidil for 3.5 years, with no side effects. He is now switching from finasteride to topical dutasteride while continuing oral minoxidil to potentially improve results further.
community [Research Breakdown] The Genetic Edge: Unpacking Dutasteride vs Finasteride Potency
Dutasteride is more effective than finasteride for increasing hair count, but finasteride is considered safer for long-term use unless hair loss is very aggressive. Starting with finasteride is recommended due to its effectiveness and safety profile.
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Frontline, gold standard treatment for combatting androgenic alopecia
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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