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forProducts matching "type i 5 alpha reductase"
Tracking 5 products like 11 Duderma, 130 UK MADE 1MG FINASTERIDE, 183 PROPECIA 1MG/*28 TABL, 183 PROPECIA 1MG/*28 TABL and 183 PROPECIA 1MG/*28 TABL from by companies like MinoxidilMax, Minoxidil Express, OnlinePharmacy-BG, Inhouse Pharmacy and oasisstad.net. View all 5 products »Learn
4 / 4 resultslearn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Metformin
diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
Research
5 / 1000+ results![Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase](/images/research/66e4646f-8129-40fe-84f0-f0d93a41b309/small/21103.jpg)
research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
![Structure of human type II 5 alpha-reductase gene](/images/research/201f02ee-9a9a-4148-a23f-8c881cf1b950/small/21118.jpg)
research Structure of human type II 5 alpha-reductase gene
The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
![Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens](/images/research/eef64229-a318-4401-9078-f2eacee058ec/small/21068.jpg)
research Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
![Effect of Sparasis crispa Extract on 5α-Reductase Gene in Dermal Papilla Cells](/images/research/46ee189d-04c9-4771-a3c3-642d9e2303ba/small/17154.jpg)
research Effect of Sparasis crispa Extract on 5α-Reductase Gene in Dermal Papilla Cells
Cauliflower Mushroom extract may help treat male hair loss by affecting hair growth-related genes.
![Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase](/images/research/5cea0dec-640c-403b-b8ad-66fc23c654fa/small/15507.jpg)
research Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
Community Join
5 / 995 resultscommunity 5ARI (dutasteride) Associated with Adverse Metabolic Effects
Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.
community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp
Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.
community FCE 28260: A Forgotten 5α-Reductase Inhibition
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community 5ar Type I in the frontal hair follicles - Dutasteride
The conversation discusses that dutasteride may be more effective than finasteride for frontal hair loss due to higher 5ar Type 1 enzyme activity in that area. Some users question the validity of this information, while others confirm it with additional sources.
community (M22) Finasteride didn’t stop my hair loss. Looks like I’ve lost the fight against MPB.
User started finasteride at 18, added minoxidil later but stopped due to side effects. Hair loss continued despite treatments, considering dutasteride but hesitant. Others suggest trying dutasteride and discussing with a dermatologist.