July 2026 in “Journal of the European Academy of Dermatology and Venereology” JAK inhibitors may reduce depression risk in alopecia areata patients.
November 2025 in “Journal of the European Academy of Dermatology and Venereology” This study found that JAK inhibitor treatment in patients with alopecia areata was associated with a lower incidence of major depressive disorder and decreased antidepressant usage.
April 2026 in “Journal of the American Academy of Dermatology” Oral 5-alpha-reductase inhibitors for hair loss don't increase heart risk.
December 2025 in “Cureus” In this retrospective cohort study, researchers found that patients with androgenetic alopecia using 5α-reductase inhibitors had a significantly higher risk of developing dry eye disease compared to those not using these medications.
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August 2024 in “International Journal of Impotence Research” In this study using the TriNetX Research Network, men with low serum testosterone levels were found to have an increased risk of developing an initial kidney stone, particularly in those aged 33-44, compared to men with normal testosterone levels.