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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  132 upvotes 1 year ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  63 upvotes 2 years ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

      community Status update on upcoming treatments

      in Treatment  53 upvotes 1 year ago
      Current treatments like finasteride, minoxidil, and derma rolling are considered the best for hair loss, while new treatments such as GT20029, PP405, and others are in various trial phases with results expected in the coming years. There is cautious optimism about the affordability and effectiveness of these upcoming treatments.

      community I can't take care of myself because of hair loss.

      in Chat  163 upvotes 1 year ago
      The conversation is about a user feeling hopeless due to hair loss despite using finasteride, dutasteride, and OM for over a year. Responses suggest therapy, self-improvement, and changing perspectives on appearance.