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research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth

101 citations, March 2019 in “Cell Stem Cell”

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

research TREM2 Macrophages Induced by Human Lipids Drive Inflammation in Acne Lesions

62 citations, July 2022 in “Science Immunology”

TREM2 macrophages and unsaturated lipids contribute to acne inflammation.

research Dermal Macrophage and Its Potential in Inducing Hair Follicle Regeneration

2 citations, March 2021 in “Molecular Immunology”

Dermal macrophages might help regrow hair.

research Keep Quiet—How Stress Regulates Hair Follicle Stem Cells

5 citations, October 2021 in “Signal Transduction and Targeted Therapy”

Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.

research Lymphatic Vasculature and Hair Follicle Regeneration

January 2022 in “Stem cell biology and regenerative medicine”

Lymphatic vessels help hair follicles regenerate by interacting with stem cells.

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community Keto 2% halted my insane shed immediately

in Ketoconazole 56 upvotes 11 months ago

Ketoconazole 2% shampoo stopped a user's severe hair shedding after just two uses, a result not achieved by finasteride or oral minoxidil. Some users suggest the shampoo's anti-androgenic properties may help with hair loss, while others think the shedding might have stopped naturally or due to the end of a shedding phase.