1 citations
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June 2025 in “Frontiers in Immunology” This study found that total serum IgE levels were elevated in patients with alopecia areata compared to controls, suggesting a possible involvement of IgE and Th2 cytokines in its pathogenesis.
10 citations
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December 2024 in “Allergy” This study found that tralokinumab effectively reduced the severity of moderate-to-severe atopic dermatitis over 28 weeks in adults, with significant improvements in clinical outcomes and biological markers, although 27.4% of patients discontinued treatment due to adverse events or ineffectiveness.
March 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case study, treatment with the selective JAK1 inhibitor upadacitinib significantly improved symptoms in a patient with refractory alopecia areata, vitiligo, ankylosing spondylitis, and allergic asthma-nasal syndrome, though a transient liver function abnormality was noted.
24 citations
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January 2012 in “Indian Journal of Dermatology, Venereology and Leprology” This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.
September 2024 in “South Eastern European Journal of Public Health” This study found that patients with alopecia areata had increased levels of serum immunoglobulin E and interleukin-13 compared to healthy controls, with additional variation in levels observed across age and weight.