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Transcription Factor SOX2-Induced Amphiregulin Inhibits Pressure Ulcer Formation via Suppressing Oxidative Stress After Cutaneous Ischemia-Reperfusion in Mice

research Transcription Factor SOX2-Induced Amphiregulin Inhibits Pressure Ulcer Formation via Suppressing Oxidative Stress After Cutaneous Ischemia-Reperfusion in Mice

April 2023 in “Journal of Investigative Dermatology”

SOX2 helps reduce wound size and pressure ulcer formation by suppressing oxidative stress and increasing antioxidant activity in mice.

research CRISPR/Cas9-Based Targeted Genome Editing for Correction of Recessive Dystrophic Epidermolysis Bullosa Using iPS Cells

1 citations, September 2019 in “Journal of Investigative Dermatology”

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

research Different Polyamine Levels in the Vertex and Occipital Hair of Pattern Hair Loss Patients

September 2019 in “Journal of Investigative Dermatology”

People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.

research Molecular Genetic Dissection of ILVEN Leads to Successful Targeted Therapy

September 2019 in “Journal of Investigative Dermatology”

Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.

research Specialized Ribosomes in Human Dermal Fibroblast Senescence

September 2019 in “Journal of Investigative Dermatology”

Specialized ribosomes affect aging in human skin cells.

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Community Join

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community Topical T3 study - 1000% Growth. Anyone tried it?

in Research/Science 106 upvotes 3 years ago

The conversation discusses using T3 (triiodothyronine) as a topical treatment for hair growth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.

community 3 months of minoxidil foam. No fin or derma rolling

in Minoxidil 700 upvotes 1 year ago

This user has had success with Minoxidil foam, achieving significant hair growth in three months without using finasteride or derma rolling. They are considering incorporating a DHT reducing strategy such as finasteride in the future.

community Take The Jump - Get The Hair Transplant

in Progress Pictures 338 upvotes 1 year ago

User got a hair transplant and it improved their life. Transplanted hair lasts, but medication like finasteride is needed to maintain non-transplanted hair.

community Phase II for Technoderma Therepeutic's TDM-105795 set to begin in April tentatively

in Research/Science 41 upvotes 1 year ago

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

community 6months update minox 5% twice daily , dermaroller 1.5mm , ketoconazole shampoo 2% 3,4 times per week and a good buzz cut LOL

in Progress Pictures 98 upvotes 2 years ago

A user's progress with hair loss treatments including minoxidil 5% twice daily, dermaroller 1.5mm, ketoconazole shampoo 2%, and a buzz cut; other users were surprised by the results as no finasteride was included in the treatment plan.

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