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Glossary Topiramate

medication used to treat epilepsy and prevent migraines

Topiramate, also known by brand names such as Topamax, is a medication primarily used to treat epilepsy and prevent migraines. It works by stabilizing electrical activity in the brain and has additional off-label uses, including for weight loss and mood stabilization.

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research Acquired trichomegaly with topiramate

24 citations , July 2005 in “Journal of the American Academy of Dermatology”

In this case report, the authors suggest that topiramate, used for treating bipolar disorder, may cause trichomegaly, or excessive eyelash growth, in patients.

research Topiramate vs Divalproex Sodium in the Preventive Treatment of Migraine: A Prospective “Real‐World” Study

19 citations , April 2011 in “Headache The Journal of Head and Face Pain”

This study found that both topiramate and divalproex sodium were similarly effective in reducing headache frequency by over 50% among episodic migraine patients after three months of treatment.

research Topiramate for Co-Occurring Bipolar Disorder and Disruptive Behavior Disorders

12 citations , August 2006 in “American Journal of Psychiatry”

Topiramate may help improve disruptive behaviors in children with bipolar disorder.

research Acneiform Rash Caused by an Unlikely Drug: Topiramate

5 citations , July 2017 in “Skin appendage disorders”

This case report describes a 35-year-old man who developed an atypical DRESS syndrome after taking topiramate for migraine prevention, which resolved with drug withdrawal and symptomatic treatment.

research Topiramate-Induced Hair Loss: Case Report

2 citations , January 2002 in “Dermatology + psychosomatics”

This case study reports that a 15-year-old girl with epilepsy experienced reversible hair loss linked to topiramate adjunctive therapy.

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