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      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

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      community Is topical fin + min having the same results as the oral one

      in General  75 upvotes 1 day ago
      Topical finasteride with minoxidil can be effective but may not match oral finasteride results, with less absorption into the bloodstream. Shedding is common when starting or stopping minoxidil and finasteride, and adding dutasteride and tretinoin can enhance effectiveness by improving absorption and DHT inhibition.

      community Topical spironolactone — how much do you apply?

      in Female  3 upvotes 2 weeks ago
      A user with androgenetic alopecia is using 8 ml of 1.4% topical spironolactone solution daily but is unsure if this amount is excessive, as 2 ml is more typical. They seek advice on the appropriate amount to apply.

      community Topical Fin 0.3/Min 6% - 11 Week progress.

      in Progress Pictures  79 upvotes 3 weeks ago
      The user applied topical finasteride 0.3% and minoxidil 6% once daily, used keto shampoo weekly, and derma stamped weekly or biweekly. They noticed hair improvement, possibly due to regrowth or letting it grow longer.

      community Topical spironolactone — how many ml do you apply?

      in Female  5 upvotes 3 weeks ago
      The conversation discusses the use of topical spironolactone for hair loss, with the original poster applying 8 ml daily but learning that 2 ml is recommended. It also touches on hair transplants and the role of DHT sensitivity in hair loss, emphasizing individual differences in treatment outcomes.