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      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

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      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 2 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Topical Saw Palmetto: An Alternative to Microdosing Topical Finasteride?

      in Product  17 upvotes 2 years ago
      The user is exploring topical Saw Palmetto as a milder alternative to microdosing topical Finasteride for hair loss, aiming to minimize systemic DHT impact. They plan to experiment with this herbal remedy for a year to assess its effectiveness on their mild androgenetic alopecia without significant side effects.

      community How to mix Viagra for topical application?

      in Treatment  6 upvotes 2 years ago
      The conversation is about experimenting with topical Viagra or Cialis for hair loss, including methods for dissolving the tablets. The user is also using herbal oil massages and considering using Ethanol/Propylene Glycol for better dissolution.

      community Best brand of topical melatonin?

      in Product  7 upvotes 3 years ago
      People are using topical melatonin for diffuse thinning and retrograde alopecia. They are discussing the best brands and application methods.