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5 / 29 resultslearn Fluridil
a topical anti-androgen with less systemic involvement
learn Spironolactone
powerful topical and oral anti-androgen used mostly by women
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
Research
5 / 1000+ resultsresearch A Mechanism for Topical Cutaneous Calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.

research Lupus Erythematosus: Considerations About Clinical, Cutaneous, and Therapeutic Aspects
Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
research Systemic and Topical Factors Involved in the Production of Experimental Cutaneous Calcinosis
Cutaneous calcinosis can be induced in young animals using certain compounds, but only in specific areas and with high mortality.

research Cutaneous Lupus Erythematosus: A Comprehensive Review
The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

research Outcome Measures in Cutaneous Autoimmune Disease: Dermatomyositis and Lupus Erythematosus
The document concludes that better tools are needed to measure skin disease severity in dermatomyositis and cutaneous lupus erythematosus, and introduces the DSSI and CLASI as reliable instruments.
Community Join
5 / 1000+ resultscommunity Scientific evidence for Peppermint & Rosemary oils + My Experience
Natural treatments for hair loss, specifically peppermint oil and rosemary oil; how they can be used as a supplementary or alternative treatment to pharmaceuticals such as finasteride and minoxidil; and the personal experience of the user Divallo, who has seen an increase in density and thickness after using these oils for around 2.5 years. The post also touches on the potential antifungal properties of the oils and their effects on cutaneous blood flow.
community Homemade topical spironolactone
The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.
community My experimental hair loss journey under medical supervision: finasteride/dutasteride, oral/topical minoxidil+tretinoin (3-month progress and hair transplant insights for those considering it)
A 23-year-old discusses their hair loss treatment using finasteride, dutasteride, oral and topical minoxidil, and topical tretinoin under medical supervision. They stress stabilizing hair loss before a hair transplant and plan to continue the regimen for at least 18 months.
community Went from almost balding to some this!
A user successfully regrew hair after nearly going bald by using oral finasteride, topical minoxidil, plasma injections, and mesotherapy over 9 months. They plan to try derma rolling and have an alarm set for taking medication, noting increased sexual drive as a side effect.
community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.