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research Topical Cyclosporine in Alopecia Areata

69 citations , February 1987 in “Archives of Dermatology”

This case report describes the topical application of cyclosporine in a man with alopecia universalis, which showed hair regrowth after 10 months of daily use, except where limited by a congenital nevus.

research Topical cyclosporine in male pattern alopecia

33 citations , February 1990 in “Journal of the American Academy of Dermatology”

Topical cyclosporine led to significant hair growth in some men with male pattern baldness.

research The effect of topical cyclosporin on the immediate shedding of human scalp hair grafted onto nude mice

23 citations , December 1988 in “British Journal of Dermatology”

This pilot study suggests that topical cyclosporin may delay hair shedding and potentially treat alopecia, based on observations in a human scalp skin graft model on mice.

research (5) Topical cyclosporin A in alopecia totalis: failure of therapeutic effect due to lack of penetration

16 citations , July 1989 in “British journal of dermatology/British journal of dermatology, Supplement”

Topical cyclosporin A doesn't work for alopecia totalis because it doesn't penetrate the skin well.

research Topical cyclosporine in alopecia areata

15 citations , February 1987 in “Archives of Dermatology”

In this case report, a 23-year-old man with alopecia universalis applied topical cyclosporine for several months, resulting in noticeable hair regrowth.

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community New topical claims complete reversal of AGA in 3 months

18 upvotes 9 years ago

A new topical treatment called RT1640 claims to reverse AGA using cyclosporine A, Minoxidil, and a new chemical entity, RT175. Users are skeptical due to lack of clinical trial data and inconsistent before-and-after photos.

community Topical Tacrolimus For Androgenetic Alopecia (AGA)

6 upvotes 1 week ago

Topical tacrolimus is being considered for androgenetic alopecia, though its effectiveness is unproven. Other treatments mentioned include minoxidil, dutasteride, cyclosporine, and teicoplanin, with discussions on blocking the prolactin receptor for hair growth.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 1 year ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

community OND-1 "Cyclosporine A” New hair loss treatment

in Research/Science 28 upvotes 5 months ago

Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

community What happened to the 40mg dutasteride daily and Cyclosporine dude?

in Chat 40 upvotes 1 year ago

A user previously claimed to take 40mg of dutasteride daily and planned to try Cyclosporine, but their account and comments have since been deleted, raising concerns about their well-being. Other users discussed the risks and effectiveness of high doses of dutasteride, with some sharing their own experiences using dutasteride, finasteride, and minoxidil for hair loss treatment.

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin mainly hydrates the hair and scalp; no study has shown that it increases hair thickness or changes follicle function.

learn Valproic acid

How is valproic acid being explored differently in topical hair products compared to its traditional oral medical use? Topical valproic acid is being studied for local effects on the hair follicle rather than the whole-body effects of the oral drug. The human evidence is one small randomized 24-week trial of an 8.3% spray; no topical valproate product is approved for hair loss.

learn Vitamin B12

Can topical products containing Vitamin B12 improve scalp health and hair growth? Topical Vitamin B12 may not significantly improve hair growth unless there's a deficiency.

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