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research Low-dose daily aspirin reduces topical minoxidil efficacy in androgenetic alopecia patients

12 citations , September 2018 in “Dermatologic Therapy”

This study found that 14 days of low-dose aspirin reduced the predicted response to topical minoxidil in androgenetic alopecia patients from 50% to 27%, suggesting aspirin may inhibit minoxidil efficacy.

Tumor Mapping in Two Large Multigenerational Families With CYLD Mutations

research Tumor Mapping in 2 Large Multigenerational Families With CYLD Mutations

44 citations , November 2009 in “Archives of Dermatology”

This study observed that patients with CYLD mutations frequently experienced severe, painful tumors beyond the head and neck, impacting their quality of life, with hormonal factors possibly contributing to tumor development.

research Festschrift in honor of the 65th birthday of Dr. Howard I. Maibach

September 1995 in “American Journal of Contact Dermatitis”

Antiyeast treatments work better for seborrheic dermatitis than steroids, and other findings include increased skin bacteria under plastic wrap, a nasal cell defect in Staphylococcus aureus carriers, quick resolution of certain skin reactions, high rubber latex allergy in spina bifida patients, and glyceryl monopentadecanoate's effectiveness for male hair loss.

research Minoxidil in the treatment of androgenetic alopecia

26 citations , August 2018 in “Dermatologic Therapy”

This review discusses the research supporting the approval and use of minoxidil for androgenic alopecia and reports no new clinical results, emphasizing recent findings and developments.

research Oral Minoxidil Therapy in Hair Loss: Where Do We Stand?

November 2023 in “Current Dermatology Reports”

This review found that oral minoxidil, particularly in low doses, is effective and safe for treating various types of hair loss, including androgenic alopecia, and may offer advantages over other treatments, such as improved convenience and enhancement of male sexual function.

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Community Join

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community No Response after 6 Months of 5 mg Oral Minoxidil

in Minoxidil 6 upvotes 1 year ago

The user experienced no response to 5 mg oral minoxidil after 6 months, with no hair regrowth or shedding. Suggestions included trying topical finasteride, dermastamping, and addressing DHT, while some users noted that factors like aspirin or Accutane might affect results.

community Daily aspirin is ruining your Min. gains

6 upvotes 3 years ago

Aspirin reduces the effectiveness of minoxidil for hair loss. Quercetin and 5-ASA medications also inhibit the necessary enzyme for minoxidil to work.

community 4 months of topical minoxidil with derma rolling starting at month 2 - my review / experience

in Is this regrowth? 45 upvotes 1 year ago

The user has been using topical minoxidil and dermarolling for hair regrowth but is hesitant to start finasteride due to potential side effects. Many suggest adding finasteride for better results in addressing DHT-related hair loss.

community Painkillers May Block Minoxidil

12 upvotes 1 year ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

community Who won’t respond to minoxidil? (Studies)

33 upvotes 6 months ago

Minoxidil's effectiveness varies due to differences in sulfotransferase enzyme levels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzyme levels.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small unblinded pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin primarily hydrates hair but does not increase thickness or follicle function.

learn L-cysteine

Can topical products with L-cysteine repair damaged hair or prevent breakage? Topical L-cysteine cannot effectively repair damaged hair or prevent breakage.

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