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research A Novel Effect of Acyclovir on Hair Growth in BALB/c Mice: A Promising Future for Finding a New Topical Drug for the Treatment of Hirsutism

1 citations , April 2020 in “Clinical, Cosmetic and Investigational Dermatology”

In this study, topical acyclovir significantly delayed hair growth initiation and completion in mice and reduced hair follicle size, suggesting potential inhibitory effects on hair growth.

research TOPICAL DELIVERY OF DRUGS USING ETHOSOMES: A REVIEW

6 citations , August 2019 in “Indian drugs”

This review discusses ethosomal delivery systems for topical drugs, highlighting their potential to improve treatment efficacy for conditions like herpes labialis and male pattern baldness, and reports no new clinical results.

research Modulation of hair growth by topical drug delivery enhanced by STAR particles

August 2023 in “Journal of controlled release”

This research found that STAR particles, ceramic particles with microneedles, significantly enhance skin permeability and improve the topical delivery of drugs like minoxidil and acyclovir, effectively promoting or inhibiting hair growth without causing skin irritation in ex vivo pig skin and rat models.

research Trichodysplasia of immunosuppression treated with oral valganciclovir

41 citations , December 2008 in “Journal of the American Academy of Dermatology”

This review discusses fixed drug eruption (FDE) potentially linked to finasteride and emphasizes dermatologists' need to recognize its possible occurrence due to the drug's widespread use, but reports no new clinical results.

research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women

7 citations , September 2013 in “Current Dermatology Reports”

This review summarizes existing literature on the safety of commonly used dermatologic medications during pregnancy but does not present new clinical findings, aiming to assist physicians with prescribing decisions.

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Community Join

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community Topical minoxidil routine and shampooing frequency

4 upvotes 3 days ago

The user applies 10% minoxidil nightly, takes 1mg finasteride, multivitamins, and a hair growth serum, and is concerned about over-washing hair with dermatologist-recommended shampoo. It is suggested to shampoo every other day and rinse with water on alternate days unless otherwise advised by a dermatologist.

community Topical min 13 months and oral fin 6 months, progress

11 upvotes 4 days ago

The user has been using topical minoxidil for 13 months and oral finasteride for 6 months to address hair loss after a hair transplant. They plan to switch to oral minoxidil for better results and occasionally use topical minoxidil and microneedling.

community F23 does Topical Min work on vellus hairs?

in Female 72 upvotes 5 days ago

Topical minoxidil 5% may help turn vellus hairs into normal-looking hairs, but results can vary, especially on the temples. The user stopped testosterone injections and finasteride, which may have affected hair recovery.

community Topical dutasteride + minox + oral fin 1mg/day

7 upvotes 5 days ago

The conversation discusses hair regrowth using topical dutasteride, minoxidil, and oral finasteride 1mg/day. The user reports seeing new hair growth.

community Topical Tacrolimus For Androgenetic Alopecia (AGA)

6 upvotes 1 week ago

Topical tacrolimus is being considered for androgenetic alopecia, though its effectiveness is unproven. Other treatments mentioned include minoxidil, dutasteride, cyclosporine, and teicoplanin, with discussions on blocking the prolactin receptor for hair growth.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin mainly hydrates the hair and scalp; no study has shown that it increases hair thickness or changes follicle function.

learn Valproic acid

How is valproic acid being explored differently in topical hair products compared to its traditional oral medical use? Topical valproic acid is being studied for local effects on the hair follicle rather than the whole-body effects of the oral drug. The human evidence is one small randomized 24-week trial of an 8.3% spray; no topical valproate product is approved for hair loss.

learn Vitamin B12

Can topical products containing Vitamin B12 improve scalp health and hair growth? Topical Vitamin B12 may not significantly improve hair growth unless there's a deficiency.

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