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    GlossaryTNF inhibitors (TNF-alpha blockers)

    medications that block inflammation-causing proteins in autoimmune diseases

    TNF inhibitors, also known as Tumor Necrosis Factor inhibitors or TNF blockers, are medications that reduce inflammation by blocking the activity of TNF-alpha, a substance in the body that causes inflammation and can lead to immune system diseases. They are commonly used to treat autoimmune conditions such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease by preventing the immune system from attacking healthy tissues.

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      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 2 weeks ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Rejected for the 2nd time for the VDPHL01 Clinical Trials (believe it or not!)

      in Chat  12 upvotes 8 months ago
      The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

      community 8 years of hair loss, turning 30 next month

      in Progress Pictures  149 upvotes 4 months ago
      The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.