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research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles

47 citations, December 2019 in “Frontiers in immunology”

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele

1 citations, August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

research Human TMEM2 Is Not a Hyaluronidase but a Regulator of Hyaluronan Metabolism

April 2023 in “Journal of Investigative Dermatology”

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

research Characterization of Novel TMEM173 Mutation Causing a Lupus- and SAVI-Like Phenotype, Modified by Polymorphisms in TMEM173 and IFIH1

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

research ST14 Interacts With TMEFF1 and Is a Predictor of Poor Prognosis in Ovarian Cancer

March 2024 in “BMC cancer”

High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.

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Community Join

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community Bro in law. Gave up because he hated dermarolling and genuinely didn't care about going bald, which he suits.

in Progress Pictures 65 upvotes 8 months ago

The conversation discusses hair loss treatment using 1ml of minoxidil twice daily and a 1.5mm dermaroller once a week. One person suggests considering finasteride, while another emphasizes the importance of microneedling in maintaining hair growth.

community Actually making progress, I think.

in Is this regrowth? 66 upvotes 5 months ago

User reports seeing fast hair regrowth after 1 month and 12 days using 0.3% Finasteride and 6% Minoxidil. They are considering microneedling and received advice to use a derma stamp.

community 4 month finasteride and minoxidil daily topical and dermastamp 1 time a week 1.25 mm

in Progress Pictures 231 upvotes 7 months ago

The conversation is about a user's four-month progress using finasteride, minoxidil, and weekly dermastamping for hair loss. People occasionally notice improvements in the user's hair.

community My hairloss journey. Minox at 34, transplant at 38. No Finasteride

in Transplants 267 upvotes 8 months ago

A person started using Minoxidil at 34 and had a hair transplant at 38, avoiding a straight hairline for a natural look and had 2200 grafts. They began taking Finasteride as a precaution, but Minoxidil did most of the work.

community Started balding at 20, tried everything, gave up. Then got a custom hair piece & it helped me embrace being bald! AMA

in Hair Systems 488 upvotes 2 years ago

A user who started balding at 20 trying different treatments to combat hair loss before eventually embracing being bald and getting a custom hair piece as an option. Various people commented on his looks with and without the wig, generally agreeing that he looked better bald.

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