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GlossaryToll-Like Receptor 2 (TLR2)

protein that detects microbial invaders and activates immune responses

Toll-Like Receptor 2 (TLR2) is a protein that plays a crucial role in the immune system by recognizing and responding to components of microbial pathogens, such as bacteria and fungi. It helps activate the body's defense mechanisms by triggering an inflammatory response, which is essential for fighting infections.

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Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity

research Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity

47 citations, June 2012 in “Genes & Development”

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

1 citations, September 2023 in “eLife”

TLR2 is important for hair growth and can be targeted to treat hair loss.

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

September 2023

TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

research TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

TLR2, a component in hair follicle stem cells, is crucial for healthy hair growth and regeneration, and its decrease can lead to hair loss.

research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology

112 citations, January 2013 in “Experimental dermatology”

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

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