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In this study on Danio rerio, researchers found that exposure to titanium dioxide nanoparticles did not affect embryonic development but altered the structure of male gonads, acting as potential endocrine disruptors with androgenic activity.

This review paper highlights that titanium dioxide nanoparticles (TiO2 NPs), due to their biological properties like antioxidant, anti-inflammatory, and antimicrobial effects, show promise in accelerating wound healing and enhancing tissue regeneration when used in scaffolds and dressings.

This chapter reviews the role of nanoparticles in wound healing, exploring current therapies, developments, and future directions, but reports no new clinical results.

This study found that nanoparticles did not permeate intact rat skin but could penetrate skin that had been artificially punctured, primarily through grooves or hair follicles.

This review discusses the challenges and contradictions in understanding nanoparticle penetration and toxicity in human skin, emphasizing the need for standardized testing and further research on particles smaller than 10 nm.