133 citations
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July 2020 in “Cells” This review discusses the modern approach of skin tissue engineering for chronic wound treatment, focusing on bioengineered artificial skin substitutes and assessing innovations in biomaterials and cell use; it reports no new clinical results.
41 citations
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June 2013 in “PLOS ONE” This study demonstrated that engineered skin substitutes using human keratinocytes and murine dermal papilla cells can develop pigmented hairs without sebaceous glands, suggesting separate pathways for hair development and eruption.
January 2026 in “Advanced Healthcare Materials” This study introduces a new multiaxial bioreactor system that uniformly stretches tissue-engineered skin grafts and improves skin tissue maturation through enhanced cellular distribution and environmental monitoring.
24 citations
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October 2010 in “Tissue Engineering Part A” This study found that tissue-engineered skin using mouse fibroblasts successfully supported hair growth after grafting, but similar success was not observed using human fibroblast-derived tissue.
11 citations
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March 2023 in “Stem Cell Research & Therapy” In this study, epidermal stem cells were found to enhance blood vessel formation and support successful one-step transplantation of tissue-engineered skin in a rat model.