3 citations
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October 2024 in “International Journal of Molecular Sciences”
This study found that in overweight or obese women with PCOS, certain baseline subcutaneous adipose tissue genes significantly predicted weight loss response to a 4-month behavioral lifestyle intervention, with the gene GSTM5 as the strongest predictor.
This study in a rat model found that dietary rehabilitation with a high protein diet reversed symptoms of kwashiorkor, suggesting a role for free radicals in its development.
January 2011 in “Zhongguo shiyong fuke yu chanke zazhi”
This study concludes that hormone therapy can significantly improve skin hydration, elasticity, thickness, and reduce wrinkles by modulating various skin cells through estrogen receptors.
Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.
Concerns about the long-term safety of VDPHL01, an extended-release minoxidil, due to potential risks similar to Cantu syndrome, were raised, highlighting the lack of monitoring for chronic connective tissuechanges. The conversation suggests that while the treatment may improve hair growth, it could lead to issues not detected in short-term trials.
Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.
Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.
A user humorously suggested smoking minoxidil in a blunt as an alternative hair growth method, sparking a satirical discussion on unconventional and unsafe ways to use minoxidil. The conversation included various suggestions like oral pills, rectal administration, and other absurd methods, with some users warning against the dangers of such practices.