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In this study, researchers differentiated induced pluripotent stem cells into cells with dermal papilla-like properties, demonstrating their potential role in hair follicle bioengineering and drug testing for hair growth.

Targeting THY1 can improve skin repair and healing.

This study found that Thy1+ keratinocytes in the basal layer of the interfollicular epidermis play a crucial role in epidermal homeostasis and wound repair, with their ablation impairing these processes.

In this study, Thy-1 was observed to play a critical role in wound healing in mice, particularly influencing vascular dynamics and blood perfusion during the healing process.

Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.