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research Keratoma Hereditaria Mutilans (Vohwinkel's Disease) with Congenital Alopecia Universalis (Atrichia Congenita)

14 citations , June 1989 in “Journal of dermatology”

This report describes the first documented occurrence of Vohwinkel's disease combined with congenital alopecia universalis in siblings from the same family, both unresponsive to prior treatments.

research Ultrastructure of the contrasting types of keratinization seen in the tail epidermis of the laboratory mouseMus musculus

11 citations , January 1977 in “Archives of dermatological research”

Mouse tail skin has different keratinization near hair follicles and scales.

research Severe, Disfiguring, Pityriasis Rubra Pilaris in a Woman in the Dominican Republic

10 citations , October 2015 in “Journal of the International Association of Providers of AIDS Care”

This case report describes a severe form of HIV-associated pityriasis rubra pilaris in a dark-skinned woman that improved rapidly and sustainably with combination antiretroviral therapy, despite atypical presentation without significant erythroderma.

research A Mouse Model for Conditional Expression of Activated β-Catenin in Epidermal Keratinocytes

1 citations , August 2024 in “Transgenic Research”

In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.

research Effects of 1?,25-dihydroxy-vitamin D3 and calcipotriol on organotypic cultures of outer root sheath cells: a potential model to evaluate antipsoriatic drugs

10 citations , October 1993 in “Archives of dermatological research”

The researchers reported that the antipsoriatic compounds 1,25-dihydroxy-vitamin D3 and calcipotriol thinned the living cell compartment in organotypic ORS cultures by accelerating the differentiation pathway rather than affecting proliferation.

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community 10+ long year fin users share your story

in Finasteride/Dutasteride 63 upvotes 1 year ago

Long-term finasteride users report maintaining or regrowing hair, often using additional treatments like minoxidil, low-level laser therapy, and ketoconazole shampoo. Most experience minimal side effects, though some report issues like erectile dysfunction.

community Can't believe I've slept on microneedling for so long.

in Microneedling 584 upvotes 1 year ago

Microneedling with minoxidil and finasteride greatly improves hair regrowth. Using 0.5mm depth every other day boosts minoxidil absorption without side effects.

community 18 months of oral Minoxidil, 5 months of Finasteride.

1155 upvotes 1 year ago

The user experienced significant hair regrowth using oral Minoxidil (5mg daily) for 18 months and Finasteride (1mg daily) for 5 months, with minimal side effects. The combination stopped hair loss and improved hair thickness, although a hair transplant is still considered for a receded hairline.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Has anyone seen progress incorporating Satanic rituals into their regimen?

467 upvotes 1 year ago

A user humorously discusses hair loss, using treatments like Dutasteride, Finasteride, Minoxidil, and RU58841, and jokingly considers satanic rituals as a solution. The conversation includes satirical responses about trading one's soul for hair.

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