February 2012 in “Hospital Pharmacy” This article discusses the importance of raising awareness about specific adverse drug reactions, methods of prevention, and the significance of reporting them to the FDA's MedWatch program, but reports no new clinical results.
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January 1977 in “PubMed” This study found that minoxidil, used with beta-blockers and thiazides, effectively reduced blood pressure in patients with severe hypertension, although it required careful management of side effects like sodium retention and increased hair growth.
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January 2018 in “Side effects of drugs annual” This review in SEDA Volume 40 summarizes new adverse reaction data for diuretics published in 2017, highlighting specific risks such as fractures with loop diuretics and hyperkalemia with spironolactone.
April 2016 in “Journal of The American Academy of Dermatology” In this study, exposure to ARBs, ACE inhibitors, and thiazides was associated with an increased risk of various skin cancers, including melanoma and nonmelanoma types, highlighting potential clinical implications for antihypertensive treatment choices.
April 2016 in “Journal of The American Academy of Dermatology” The researchers reported an increased risk of malignant melanoma and nonmelanoma skin cancers with the use of angiotensin-receptor blockers, angiotensin-converting enzyme inhibitors, and thiazides in a large patient study.