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Pharmacological Activation of Thermo-Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

research Pharmacological Activation of Thermo-Transient Receptor Potential Vanilloid 3 Channels Inhibits Hair Growth by Inducing Cell Death of Hair Follicle Outer Root Sheath

12 citations, May 2019 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

research Pathogenesis and Management of TRPV3-Related Olmsted Syndrome

December 2024 in “Frontiers in Genetics”

EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.

research TRPV3 Ion Channel: From Gene to Pharmacology

2 citations, May 2023 in “International Journal of Molecular Sciences”

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

research TRP Channels in Skin Biology and Pathophysiology

124 citations, December 2016 in “Pharmaceuticals”

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

research Transient Stimulation of TRPV4-Expressing Keratinocytes Promotes Hair Follicle Regeneration in Mice

4 citations, June 2020 in “British Journal of Pharmacology”

Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.

View more "thermo transient receptor potential vanilloid 3" in research →

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community Looking to make my own 2-Deoxy-D-ribose. Any science bros can give advice?

in Research/Science 7 upvotes 5 months ago

A user is making a 2-Deoxy-D-ribose solution and asks if it can be put into an oil instead of a gel, considering adding hydrocortisone and retinoic acid. They seek advice on the best carrier oil for hair growth.

community New drug for hair loss announced by Amplifica

in Research/Science 161 upvotes 1 year ago

Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.

community Why I Will be Accepting Baldness

in Chat 204 upvotes 1 year ago

User decides to accept baldness due to mental health issues with finasteride. Others suggest considering hair systems, topical finasteride, or RU58841 as alternatives.

community Thoughts on Finasteride and Sexual Side Effects

in Finasteride 51 upvotes 5 years ago

A user discusses starting finasteride for hair loss despite concerns about potential sexual side effects, emphasizing the psychological factors involved. Other users share mixed experiences, with some reporting no side effects and others experiencing issues.