August 2025 in “Arabixiv (OSF Preprints)” This study suggests that male pattern baldness is primarily caused by heat stress in the brain rather than DHT toxicity, and personal experiments with menthol cooling have shown significant reduction in hair loss.
15 citations
,
January 1998 This study found that repeated cycles of wetting and blow-drying hair fibers can cause cracks in the hair cuticles, particularly among individuals who frequently blow-dry their hair.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduces a hypothesis that elevated DHT at puberty may cause chronic thermal stress in specific scalp areas, potentially explaining Androgenetic Alopecia characteristics and guiding future research.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper introduces a hypothesis that elevated DHT at puberty may increase cerebral heat output, creating chronic thermal stress linked to androgenetic alopecia, and suggests this could be tested with MR thermometry.
88 citations
,
August 2014 in “PLOS genetics” This study found that mice lacking syndecan-1 experienced cold stress and metabolic issues due to reduced intradermal fat, which was restored by thermoneutral housing or rosiglitazone treatment.