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GlossaryTransforming Growth Factor Beta Receptor 1 (TGFBR1)

protein involved in cell signaling and regulating growth

Transforming Growth Factor Beta Receptor 1 (TGFBR1) is a protein that plays a crucial role in cell signaling, particularly in regulating cell growth, differentiation, and immune responses. It is part of the TGF-beta signaling pathway, which is important for maintaining tissue homeostasis and has been implicated in various conditions, including cancer, fibrosis, and alopecia.

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research TGFβ and Cancer Metastasis: An Inflammation Link

55 citations, April 2010 in “Cancer and Metastasis Reviews”

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle

417 citations, September 2005 in “PLoS biology”

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

research The Rotterdam Study: 2014 Objectives and Design Update

266 citations, November 2013 in “European Journal of Epidemiology”

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

research Regulatory T Cells: The Many Faces of Foxp3

125 citations, September 2019 in “Journal of Clinical Immunology”

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

research Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair

124 citations, June 2020 in “Cell Stem Cell”

Fat cells in the skin help start healing and form important repair cells after injury.

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