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Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes

research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes

54 citations, November 2017 in “Scientific Reports”

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

research The Regeneration Blastema of Lizards: An Amniote Model for the Study of Appendage Replacement

39 citations, April 2015 in “Regeneration”

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

research Comparative Study on Seasonal Hair Follicle Cycling by Analysis of the Transcriptomes from Cashmere and Milk Goats

25 citations, February 2019 in “Genomics”

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

research Estrogen Modulates Mesenchymal-Epidermal Interactions in the Adult Nipple

4 citations, March 2017 in “Development”

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

research Role of Stem/Progenitor Cells in Reparative Disorders

29 citations, December 2012 in “Fibrogenesis & Tissue Repair”

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

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community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 37 upvotes 1 year ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 668 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 441 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

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