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Sexually Dimorphic Effect of Progesterone and Its Reduced Metabolites on the Gene Expression of Myelin Proteins in Rat Schwann Cells

research Sexually Dimorphic Effect of Progesterone and Its Reduced Metabolites on the Gene Expression of Myelin Proteins in Rat Schwann Cells

May 2006 in “Frontiers in Neuroendocrinology”

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.

research Reduced Metabolites Mediate Neuroprotective Effects of Progesterone in the Adult Rat Hippocampus. The Synthetic Progestin Medroxyprogesterone Acetate (Provera) Is Not Neuroprotective

123 citations , June 2006 in “Journal of Neurobiology”

Progesterone protects brain cells, but Provera does not.

research Isotope Dilution-Based Targeted and Nontargeted Carbonyl Neurosteroid/Steroid Profiling

12 citations , March 2018 in “Analytical chemistry”

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

research Progesterone and Its Metabolites: Anticonvulsant and Behavioral Studies

June 2014 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)”

Progesterone and its metabolites can prevent seizures without major side effects.

research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride

137 citations , March 2006 in “Cns Drug Reviews”

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

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community 18M 8 months progress 40mg daily dut stack

in Progress Pictures 112 upvotes 7 months ago

An 18-year-old is using a high-dose hair loss treatment with 40mg daily dutasteride, finasteride, minoxidil, tretinoin, and topical bicalutamide. Despite health risk concerns, especially liver issues, they report hair regrowth progress and intend to continue the regimen.

community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 38 upvotes 6 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.