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Comparative Analysis of Temperature-Controlled Cryotherapy Versus Intralesional Triamcinolone Acetonide Injection for Alopecia Areata: An Intrasubject Split-Lesion Pilot Study

research Comparative analysis of temperature‐controlled cryotherapy versus intralesional triamcinolone acetonide injection for alopecia areata: An intrasubject split‐lesion pilot study

November 2024 in “Journal of the European Academy of Dermatology and Venereology”

In this pilot study, cryotherapy using a device that precisely controls cooling duration improved hair regrowth for patchy alopecia areata when applied for 20 seconds with two freeze-thaw cycles, similar to standard triamcinolone acetonide injections, but not when applied for 10 seconds.

research Cell surface receptor kinase FERONIA linked to nutrient sensor TORC signaling controls root hair growth at low temperature linked to low nitrate in Arabidopsis thaliana

44 citations , January 2023 in “New Phytologist”

This study found that low temperature triggers root hair elongation in Arabidopsis thaliana through a FERONIA-ROP2-TORC signaling pathway, also activated by nitrogen deficiency.

Cell Surface Receptor Kinase FERONIA Linked to Nutrient Sensor TORC Signaling Controls Root Hair Growth at Low Temperature Linked to Low Nitrate in Arabidopsis Thaliana

research Cell surface receptor kinase FERONIA linked to nutrient sensor TORC signaling controls root hair growth at low temperature linked to low nitrate inArabidopsis thaliana

2 citations , January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.

Nature-Skin-Based Multi-Responsive Controlled-Release Electroactive Scaffolds for Integrated Melanoma Postoperative Relapse Prevention and Wound Therapy

research Nature-skin-based multi-responsive controlled-release electroactive scaffolds for integrated melanoma postoperative relapse prevention and wound therapy

2 citations , February 2023 in “Research Square (Research Square)”

In this study, a newly engineered scaffold, PADM-MX-Ag-Si@Dox, demonstrated potential as a multifunctional biomaterial for postoperative melanoma treatment by controlling drug release, enhancing wound healing, and enabling real-time tumor surveillance through temperature, pH, and electrical stimuli.

research Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle

62 citations , November 2016 in “Nanoscale”

In this study, researchers developed thermoresponsive nanogels that effectively penetrate hair follicles and release a model drug when triggered by temperature, demonstrating greater penetration for medium to large nanogels (300–500 nm) compared to smaller ones.

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community Minoxidil cannot survive summer in warehouses or UPS trucks

64 upvotes 1 month ago

Minoxidil's effectiveness may not be significantly impacted by high temperatures during shipping, as it undergoes stability tests to withstand extreme conditions. Users discuss concerns about oxidation and storage, but experts suggest that short-term exposure to heat is unlikely to degrade the product.

community For those of your wondering whether RU is shelf stable or needs to be refrigerated, here's some info from one of the online retailers that I received asking about this specific subject

in Treatment 3 upvotes 5 months ago

RU58841 should be stored in the refrigerator to maintain efficacy, but it remains stable for over two years even without refrigeration. A user prefers using Minoxidil and finasteride instead.

community Are PP405 and JXL069 the same ?

2 upvotes 1 month ago

PP405 and JXL069 are the same active molecule, suvomipic, but differ in effectiveness due to delivery methods. Grey market versions fail due to improper formulation and stability issues, unlike the clinically engineered Pelage Pharmaceuticals version.

community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

17 upvotes 10 months ago

A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.

community My Fin and Min journey so far (1 year progress)

397 upvotes 11 months ago

The user experienced hair regrowth using 2.5mg finasteride daily and by drinking topical minoxidil mixed with water. Commenters advised against this method, suggesting oral minoxidil for safety.

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