November 2025 in “Scientific Reports” This study found that a blink frequency of at least 20 blinks per minute is necessary to maintain tear film stability in young participants with dry eye symptoms, with lower frequencies significantly worsening various indicators of eye dryness.
1 citations
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October 2025 in “Transfusion Medicine and Hemotherapy” This review synthesizes current evidence on platelet-rich plasma for dry eye disease and reports no new results; the authors emphasize the need for standardized trials to validate these approaches.
27 citations
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January 2016 in “Cellular Physiology and Biochemistry” This study found that the extract of Bidens pilosa L. improved dry eye symptoms associated with androgen deficiency in rats by enhancing tear production, stabilizing the tear film, and reducing lacrimal gland inflammation.
4 citations
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January 2021 in “Dermatology Review” This review discusses the role of Demodex mites in ocular demodecosis and various eye ailments, highlighting diagnostic methods but noting a lack of standardized treatments, with no new clinical results reported.
18 citations
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March 2014 in “Journal of Pharmacological and Toxicological Methods” This study found that ovariectomized and finasteride-treated rats showed significant tear film deficiency and downregulation of sex steroid receptors in ocular tissues, suggesting potential models for studying dry eye disorders.